The Impact of Two Platelet Concentrates on Healing of Surgically Created Bone Defects in Sheep (Radiological Analysis)
Abstract
The present study aims to assess the density of bone with Concentrated growth factors and advanced plasma-rich fibrin in the bone defects that were created surgically in the sheeps mandible by the use of radiographic assessment. Materials and methods: Seven defects were made in the bone with 4 mm depth and width on every side of the mandible of the eight sheep, The defects were filled in the following manner: from the proximal to the distal orientation; 1st, 2nd, 3rd, 4th, and the 5th defect was full of CGF on the right side and A-FRF is in the left side, the 6th, and 7th left empty to filled with physiological clot. Densitometric analysis of the defects of the bone was made to measure the bone density of the 4 intervals (3 days, 7 days, 21 days, 28 days), after the surgery. Results: The result of the Densitometric analysis revealed a major distinction between the CGF group and the A-PRF group when compared to the control group at all four intervals with the density of the bone being the highest in the CGF group followed by the A-PRF group and the control group was the least one show improvement in the bone density. Conclusions: The CGF group increased the density of the bone throughout the entire study period as found by densitometric analysis data.
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