Since the independence of the United States of America in 1781 AD, American interests in the Middle East, in general, and the Ottoman Empire, in particular, began. In various economic, political and cultural levels, and this is due to the sense of successive US administrations of the strategic importance of the region, and the importance of the topic stems from being a study of the roots of the American policy towards the Ottoman state and its developments during an important stage of the long life of the Ottoman Empire, represented by the nineteenth century AD. The century is the great start for the United States in its economic development and its direction towards the outside world for trade and colonialism together. The Ottoman Empire was very important in planning the American capitalists, as it represented a strategic meeting place for all the continents of the ancient world and an important commercial hub for the whole world.