This search is a study of residential and settling diseases like malaria, bilharziasis, fever, T.B and leprosy. It aims at standing on its economical and residential traces through studying of many cities and districts of Islamic states. They are studied by many historical and geographical references and other authorities. It also attempts the attempting to know the factors which helped behind spreading of these diseases. It is to be geographical factors noted that came at the leading position of the sefactors factors. Cause The geographical environment plays a role in existing these diseases. Similarly the weather and its changes time and its change.within the seasons Changer in temperatures, moisture and winds. Partrcularly could be a logical reasons.In addition to another factors like carelessnes in the sanitary supplements especially the system of draining and water canals and internal draining, beside to the floods that happened. The refore, great areas summarize them were overflown with water .This paper has come up with important results and we can in the following points:1. Diseases have great effect in the life of people and in the economical affairs for these societies because they have continuous effect.2. Huge statistical in figures Mortality were recoededin the year which the diseases became active.3. Reduction in production in the effected areas by these diseases, and weakening the abilities of those who infected by this disease to work and produce.4. Many diseases have great impact on agriculture and its expanision in especially malaria and bilharziasis.5. leaving planting many kinds of crops because its connection with many insects which caused disease, like rise planting and its connection with existence of bilharziasis worm which causes the disease.6. Effectting on the averages of morbidity and residential growing.