Assessment of Remineralizing Effect of Silver Diamine Fluoride(SDF) with Depigmented agent s on Demineralized enamel surface of permanent teeth (in Vitro Study)

Background: Management of dental caries is the most challenging disease since it needs an innovative approach for treatment or preventive measures. Recently professionals have been using silver diamine fluoride as an arresting agent for dental caries. Aims: Comparing the effect ofthe application of 38% Silver diamine fluoride (SDF)on the microhardness of artificially induced enamel surface caries of permanent teeth, with sodium fluoride and de-ionized water by Vickers micro-hardness, and scanning electron microscope (SEM), also testing whether the depigmented agent added to 38% silver diamine fluoride affecting the microhardness of artificially induced caries. Materials and methods: The samples consisted of 45 sound maxillary first premolars; the sample was divided randomly into five groups after they were subjected to a freshly prepared demineralizing agent for 4 successive days, each group consisted of 9 teeth. Group1: demineralization then treated with 38% of SDF with potassium iodide (kl) for 1 hour, Croup2: demineralization then treated with 38% of SDF with glutathione (20% GSH) for 1 hour, Group3: demineralization then treated with 38% of SDF alone for 1 hour, Group4: demineralization then treated with 5% of sodium fluoride for 1 hour (positive control), Group5: demineralization then socked in de-ionized water for the rest of the experiment (negative control). Result: There were statistical differences among all groups after treatment with a remineralizing agent. The microhardness value shows statistically significant differences in which the highest increase was in the SDF alone group, followed by Silver diamine fluoride with potassium iodide, silver diamine fluoride with glutathione, and sodium fluoride respectively, and finally, the deionized water group which has the least means of microhardness. Conclusion: SDF material is effective in arresting initial enamel caries of permanent teeth.