This study, titled (Value Contention from the Perspective of the Holy Quran), aims to clarify the concept of values and its relationship to the Sunnah of human, civilizational and intellectual contention (tadafu) and conflict in the lives of individuals, societies or human civilizations, adopting an inductive and analytical approach. The goal is to reach a clear understanding about the concept of values on the one hand, and the value contention on the other hand. The first section of the study contains the linguistic definition of values and their meanings in the Holy Quran according to various contexts. Values have also been defined according to other fields because they are among the concepts that are connected to many areas, such as religion, philosophy and sociology. The second section is dedicated for explaining the reality of the value contention from the perspective of the Holy Quran, which is a part of the divine cosmic Sunnah of contention (tadafu). The Holy Quran mentioned to the story of the first contention (tadafu) among the humanity (the contention of the two sons of Adam). The discussion and conflict that took place between the two sons of Adam was nothing but a kind of contention between the different values that each of them embraced. The murderer (Cain) had no values that would prevent him from attacking his brother. As for the murdered (Abel), his positive behavior resulted from virtuous values that encouraged him to take another path in his struggle with his brother. The struggle of the unbelievers with the Prophet (peace be upon Him) was a struggle between the Islamic values that the Islamic message carried, and the values of paganism, ignorance and slavery. Likewise, the struggle of ancient peoples and nations with the prophets and Muslims is nothing but a struggle between different values. The summary is that values were and still are a cause of the causes of contention and conflict between man, and this is an inevitable Sunnah that God's wisdom required it to be.