The research deals with the most important and important economic crises that hit the region of Mosul and the island of Euphrates, which was unveiled in the historical Syria sources during the period from the second century AH / 8th century to the seventh century AH / thirteenth century AD. We have been keen in this modest research to cite the most important reasons that led to these crises as well as we dealt with the most important negative consequences that left in the economic aspects and social effects. The important thing that must be mentioned that the Syria historical sources often differed in mentioning information of a economic nature from what was mentioned by the mothers of Islamic sources, this will be explained later.