Synthesis of some Derivatives 2-Aryl -1,3,4-Thiadiazoline-2-One

To synthesis of some new heterocyclic compounds containing 1,3,4-thiadiazole moieties. Many of 5-alkyl-3-(4-substituted-2-butyn-1-yl) -1,3,4-thiadaizoline-2(3H)-one (15a-e and 16a-e) have been prepared by the reactions sequences starting from the acid hydrazides (1 and 2). All the products are well known for their useful biological activities. The structures of all compounds were confirmed by physical and spectral methods