Synthesis, Characterization of some new Heterocyclic Compounds Derived from Chalcones Containing Schiff Bases

Section: Research Paper
Published
Jun 24, 2025
Pages
127-137

Abstract

The present work involves the new chalcones containing Schiff bases, In this study, firstly, reaction of 3-acetylcoumarin with terephthaldehyde to prepared chalcones which contains a free aldehyde group which has been reacted with (4-Aminoantipyrine) to prepare Schiff bases, which was reacted (sodiumazide) as precursor to form (Tetrazole) followed by condensation of these chalcones with some compounds (hydroxylamine, aminophenol, phenylenediamine, hydrazine, semicar- bazide, thiosemicarbazide, urea, thiourea and quanidine) as precursor to form Isoxazole, oxazepane, diazepine, pyrazoles and pyrimidine derivatives in basic medium using classical and ultrasonic technique. The comparison of the classical methods with ultrasonic methods. Was achieved. The compositions of the prepared compounds were confirmed by FT- IR and1H NMR spectroscopy.

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How to Cite

Ghanim, tharee, & O. Omar, A. (2025). Synthesis, Characterization of some new Heterocyclic Compounds Derived from Chalcones Containing Schiff Bases. Rafidain Journal of Science, 32(1), 127–137. https://doi.org/10.33899/rjs.2023.177295