Antimutagenic Effects of the Alcoholic Extracts of Cyperus rotandus Tuber and Salvia officinalis Leaves in Aspergillus amstelodami

This study involved testing the antimutagenic effect of three concentrations of the alcoholic extract of Cyperus rotandus tuber and of Salvia officinalis leaves. The concentrations were (800, 900 and 1000) (500, 700 and 900) mg/ml respectively in conidia of fungus Aspergillus amstelodami. The antimutagenic action was tested by checking the ability of both extract to reduce the frequency of mutation resistant benomyl induced by nitrous acid, in the conidia treated with nitrous acid for 15, 30, 45 and 60 minutes. The combination between the mutagen and the extract were tested by (Using extract after treating the conidia with mutagen E/N, using mutagen and extract together N+E). Alcoholic extract of both tuber Cyperus rotandus and leaves of Salvia officinalis reduced the mutagenicity of nitrous acid but to different extents.