Central Precocious Puberty as a Complication of Peripheral Precocious Puberty due to Congenital Adrenal Hyperplasia in a Boy: A Case Report from Iraq

The transition from peripheral to central precocious puberty may occur from prolonged exposure to sex hormones from gonadotropin-releasing hormone-independent etiologies, including congenital adrenal hyperplasia. Herby, we present a case report in a 6-year-old and 5-month-old boy with congenital adrenal hyperplasia developing into central precocious puberty preceded by peripheral precocious puberty. Early detection and therapy of precocious puberty due to congenital adrenal hyperplasia should begin as soon as feasible because failure to do so may result in short stature and other long-term mental and physical consequences.