Volume 11 Issue 2
Published: 2011-12-01
Contents
Article
Synthesis and in vitro kinetic study of novel mutual azo prodrug for inflammatory bowel disease
Yasser Fakri Mustafa
Background: Inflammatory bowel disease (IBD) refers to idiopathic inflammatorydiseases of the intestine, principally ulcerative colitis and Crohns disease. IBD ischaracterized by chronic...
Assessment of serum carcinoembryonic antigen in colorectal cancer patients treated by surgery and chemotherapy
Shahbaa A. Al-Bayati
Objective: Carcinoembryonic antigen (CEA) is a protein found in many types of cellsassociated with tumors and the developing fetus. The main use of CEA is as a tumormarker, especially with...
Preparation of modified release diltiazem HCl capsule by complexation with ion exchange resin
Eman B.H. Al-Khedairy, Alaa A. Abdulrasso, Jenan M. AL-Mosawi
Background: Diltiazem HCl is a calcium channel blocker drug used in the treatmentof angina pectoris and hypertension.Objective: To prepare a sustained release diltiazem HCl capsule by...
The effect of antioxidant supplementation in the treatment of epilepsy
Nazar A.K. hamid
Aim: To assess serum level of malondialdehyde (MDA) and total antioxidant status(TAS) as a representative of oxidative stress in patients with generalized epilepsy andto evaluate the therapeutic...
The effect of rifampicin and isoniazid on liver and lung tissues in rats
Dalal F. Ahmed
Objectives: The purpose of this study was to investigate the histopathologicalchanges in Swiss albino rats liver and lung tissues resulted from the oraladministration of the antituberculous drugs...
Effects of estrogen replacement therapy on symptoms and clinical parameters in post menopausal women
Norjihan Ali Shaban, Kawa Dizaye
Objective: To evaluate the effect of oral estrogen replacement therapy (ERT) in healthypostmenopausal women on lipid profile, body mass index (BMI), blood pressure, andblood glucose; and on...
Synthesis of new metoclopramide derivatives and in vitro evaluation of their human cholinesterases protection against Chlorpyrifos
Islam Tarik Qasim, Ahmed A.J. Mahmood, Yasser Fakri Mustafa
Objective: The purpose of this study was to synthesize three new derivatives ofmetoclopramide by diazotization and replacement reactions and then to quantify invitro their protection effects on...
Cerebrospinal fluid cholinesterase activity in children with meningitis
Aldeen Alnoori, Mohammed Khalid Jamal
Objective: To assess the changes of cerebrospinal fluid (CSF) acetyl cholinesterase(AChE) activity in children with acute bacterial meningitis in comparison to healthyage and sex matched...
Indirect spectrophotometric method for the determination of bisacodyl in commercial dosage forms and in environmental water samples
Nawal A. Majid, Nief Rahman Ahmad
Objective: A simple, sensitive, and accurate indirect spectrophotometric method forthe determination of bisacodyl in pure form and in some of its pharmaceuticalpreparations.Method: The method is...
Detection of Toxoplasma gondii IgM and Cytomegalovirus IgM antibodies among blood donors in Mosul
Karam A. Al-Dabbagh
Background: Toxoplasmosis is an infection caused by the protozoan parasiteToxoplasma gondii. This parasite can be transmitted via blood transfusion.Cytomegalovirus (CMV) is a herpes virus that can...
In vitro kinetic study of donepezil N- oxide metabolites
Faris T. Abachi, Ammar B. Behnan, Riyath A. Atto
Objective: The aim of this study was to examine the metabolism of donepezil via N oxidation of donepezil HCl in vitro, and the kinetic studies at a temperature similarto that of the human...
Comparison between quantitative and qualitative biochemical markers in the diagnosis of acute coronary syndrome
Akram J Ahmad, Samir B Al-Mukhtar
Objectives: To compare between the qualitative estimation of biochemical markersPoint-of-Care testing) with the quantitative estimation of the same markers in thediagnosis of acute coronary...
Serum immunoglobulin levels in male schizophrenic patients before and after olanzapine therapy
Mahmoud Khudhayer Oglah Hussein
Objective: To evaluate the effect of olanzapine therapy on serum immunoglobulinlevels (IgA, IgG, IgM) in male schizophrenic patients after 2 months of treatment byolanzapine at a daily dose of 20...
