Volume 20 Issue

Published: 2023-12-01

Contents


Research Paper
Systemic Adverse Effects of Topical Clobetasol and Counterfeit Cosmetic Products on Iraqi Women

Teeba H. Sagban, Ausama Ayob Jaccob, Abdulla Ayob Yaqoub, Huda Khadim

Background: Topical corticosteroids (TCs) are widely used for dermatologic diseases. Unfortunately, there exists many adverse effects (local and systemic). These adverse effects are comparable to...

DOI: 10.33899/iphr.2023.143457.1061

Pages: 201-209
Evaluation of Various In-vitro Biological Activities of Crude Quince Seed Ethanolic Extract

Raghad Riyadh Khalil

Background: for a long time, natural bio-actives have been used to treat, cure, and prevent illnesses. Fruit seed crude extracts have been found to have various beneficial biological activities,...

DOI: 10.33899/iphr.2023.144158.1063

Pages: 217-223
Exploring the Antimicrobial Activity of Quince Seeds Extracted by Two Different Methods

Eman Tareq Mohammed

Background: The rise of resistance to numerous effective antimicrobic drugs and the necessity to investigate alternative agents to address this emerge are conspicuously underscored. Aim: The aim is...

DOI: 10.33899/iphr.2023.144159.1064

Pages: 224-235
Thermosonication-Catalyzed Synthesis of New 3-Esterified Coumarins as Biocompatible Antitumor Candidates

Sawsan Hasan Hammodi

Background: Coumarin chemical moiety and its-based molecules attracted a lot of research attention by chemists of natural products and organic synthesis. This attention works in two directions:...

DOI: 10.33899/iphr.2023.144182.1066

Pages: 236-242
Histological and Morphometric Effect of Amiodarone on the Ovary in Adult Female Albino Rats

Zahraa Abd-Alkader Taboo

Background and objectives: Amiodarone is an antiarrhythmic medication used to treat abnormal heart rhythms. This study aimed to analyse the histological variations in ovarian follicles of rats...

DOI: 10.33899/iphr.2023.144294.1067

Pages: 243-249
Review Paper
Synthesis and Pharmacological Profiles of 6,7-Dihydroxycoumarin and Its Derivatives: A Concise Review

Yasser Fakri Mustafa, Nameer Mazin Zeki

Background: Esculetin, scientifically referred to as 6,7-dihydroxycoumarin, functions as the primary bioactive constituent found in Cortex Fraxini (commonly known as ash bark), an ancient Asian...

DOI: 10.33899/iphr.2023.143017.1059

Pages: 174-188
Statin Gastroprotective Mechanisms Independent of Gastric Acid Suppression

Hani M. Almukhtar, Dilgash A Abdullah

Background: Statins have demonstrated various beneficial clinical outcomes, not only in patients with elevated cholesterol levels but also in those with normal levels, a collective phenomenon known...

DOI: 10.33899/iphr.2023.142864.1056

Pages: 189-194
Mirabegron-Induced Smooth Muscle Relaxation: Review of the Suggested Mechanisms

Rahma Saadaldain Almallah, Hani M. Almukhtar

Background: Mirabegron operates through a distinct mechanism compared to antimuscarinic agents. Its activation of 3-adrenoceptors results in the relaxation of the bladder during the filling phase...

DOI: 10.33899/iphr.2023.142851.1057

Pages: 195-200
The Effect of Cilnidipine on Insulin Sensitivity

Maha Abdalwahab Mahmood, Shatha Hani Mohammad

Background: Cilnidipine, a common hypertension medication, is now being studied for its potential to improve insulin sensitivity, which plays a key role in regulating blood sugar levels. Recent...

DOI: 10.33899/iphr.2023.143299.1060

Pages: 210-216
Angiotensin-Converting Enzyme Inhibitors and Adipokines: The Role of Visfatin and Apelin in Cardiovascular Disease Management

Yaseen Khamees Jumaah, Zainab Haitham Fathi, Jehan Abdulwahab Mohammad

Background: Angiotensin-converting enzyme (ACE) Inhibitors are medications pivotal in cardiovascular disease management, impacting the renin-angiotensin system which plays a critical role in...

DOI: 10.33899/iphr.2023.143923.1062

Pages: 250-260