Volume 18 Issue 2
Published: 2021-12-01
Contents
Research Paper
Evaluation of cytogenetic damage induced by antihypertensive drug Amlodipine: in vitro
Dian J. Salih, Sayran K. Salih, Rawaa M. Abdo, Asaad A. Alasady
Background: Amlodipine is a calcium channel blocker medication used to treat high blood pressure and coronary artery diseases for long term of use. Sufficient studies reporting the cytogenetic...
DOI: 10.33899/iphr.2022.170390
Antibacterial activities of plant extract Cinnamomum zeylanicum bark against multidrug-resistant bacteria
Nishteman F. Mohammad, Shilan S. Saleem, Rand B. Balata, Dian J. Salih
Background : Due to the increased occurrence of bacterial resistance to multiple antimicrobial drugs, there is a constant search for novel therapeutic strategies; medicinal plants represent an...
DOI: 10.33899/iphr.2022.170393
Formulation and Evaluation of Rosuvastatin Calcium Polymeric Nanoparticles-Loaded Transdermal Patch
Mais S. Saadallah, Omar A. Hamid
Background: Transdermal drug delivery systems (TDDS) have been rapidly developed as a promising alternative to the oral delivery systems to provide controlled drug delivery and avoid the first-pass...
DOI: 10.33899/iphr.2022.170395
Preparation and Evaluation of Topical Gel Containing Aloe Vera Exudate
Amina Mudhafar Al-Nima
Background:Aloe vera is known as a miracle plant belonging to the Lily (Liliaceae) family, The exudate of Aloe vera is utilized as a natural drug as it can be used for many medicinal purposes.Aims:...
DOI: 10.33899/iphr.2022.170396
Review Paper
Minoxidil in androgenic alopecia: New formulations with Improved delivery
Alaa Al-taie, Myasar M. Al-kotaji, Hani M. Almukhtar
Background: Minoxidil was introduced into the market as a hypotensive agent, however, aftermarketing, the hypertrichosis side effect was reported by almost all users. This adverse effect encourages...
DOI: 10.33899/iphr.2022.170397
Transdermal patch of acetylsalicylic acid as an alternative dosage form: A review
Hayder F. Alhamdany, Mohanad A. Alfahad
As a substitute for traditional systemic administration, many topical treatments have lately evolved. Transdermal drug delivery systems (TDDSs) are the most appealing of these methods due to their...
DOI: 10.33899/iphr.2022.170398
Effect of polyphenol secondary metabolites on oxidative stress and inflammatory responses associated with aging diseases
Khadeeja Y. Abid, Maimonah Qasim Yahya, Adnan A. Zainal
Several mechanisms are responsible for regulating the process of aging. A rise in reactive oxygen species (ROS) and oxidative stress is usually linked to the development of age-related diseases....
DOI: 10.33899/iphr.2022.170399
Bacteriophage as a Promising Alternative or Complementary Therapy to Antibiotics
Zahraa A. Hashim, Farah H. Omer
The global issue of antibiotic resistance and the narrowing down of new antibiotic discoveries besides their cost has led to the reintroduction of bacteriophage as a focus of research projects....
DOI: 10.33899/iphr.2022.170408
Drug Physicochemical Properties Relevant to Powder Flowability in Pharmaceutical Appliance: A Review
Liqaa S. Esmail
Background: Studies have shown that the powder flowability rate significantly impacts the content uniformity and weight of the active pharmaceutical ingredients in drug tableting procedures.The aim...
DOI: 10.33899/iphr.2022.170401
A review on coumarin backbone: An attractive scaffold for promising bioactive compounds
Yasser F. Mustafa, Sara F. Jasim
Background: Coumarin moiety is found in many naturally occurring products that have been used for many decades in traditional medicine around the world. Coumarin has distinctive physicochemical...
DOI: 10.33899/iphr.2022.170402
Synthesis of coumarin-based derivatives from different starting materials: A review of ongoing developments
Yasser F. Mustafa, Sarah A. Waheed
Objective: This brief review highlights the recent advances in the synthesis of coumarin-based derivatives from phenols, aldehydes, ketones, and various other functional group-containing starting...
DOI: 10.33899/iphr.2022.170403
Natural Coumarin-Lead Compounds: A Review of Their Medicinal Potentials
Yasser F. Mustafa, Rahma M. Jebir
Background: Natural coumarins group, a principal member of the benzopyrone family, is one of the naturally occurring substances obtained ordinarily from plant origins, with antibacterial,...
DOI: 10.33899/iphr.2022.170404
Coumarin-based products: Their biodiversity and pharmacology
Yasser F. Mustafa, Reem N. Ismael, Harith K. Al-Qazaz
Background: The plant kingdom generates and releases a wide range of secondary-metabolites, which have several effects on biological, toxicological, and ecological systems that may act in a similar...
DOI: 10.33899/iphr.2022.170405
Green synthesis of Schiff bases: a review study
Ahmed A. Mahmood
Objectives: Green chemistry is the field that implies instruments and procedures, by which it offers significant environmental and financial benefits above traditional synthetic methods. The modern...
DOI: 10.33899/iphr.2022.170406
Drug Abuse as a Contemporary Social Problem
Zena S. Hamed
Objective: Drug abuse and its repercussions are of the most serious problems in society nowadays. This is because of their enormous influence on the individual, the family, and its social effects...
DOI: 10.33899/iphr.2022.170407
